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S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications

Osteosarcoma (OS) is an aggressive and highly metastatic form of primary bone cancer affecting young children and adults. Previous studies have shown that hypomethylation of critical genes is driving metastasis. Here, we examine whether hypermethylation treatment can block OS growth and pulmonary me...

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Detalles Bibliográficos
Autores principales:	Parashar, Surabhi, Cheishvili, David, Arakelian, Ani, Hussain, Zahid, Tanvir, Imrana, Khan, Haseeb Ahmed, Szyf, Moshe, Rabbani, Shafaat A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430266/ https://www.ncbi.nlm.nih.gov/pubmed/25619880 http://dx.doi.org/10.1002/cam4.386

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