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Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis

Hypoxia is a common feature of locally advanced breast cancers and is associated with increased metastasis and poorer survival. Stabilisation of Hypoxia-Inducible Factor-1α (HIF1α) in tumours causes transcriptional changes in numerous genes that function at distinct stages of the metastatic cascade....

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Detalles Bibliográficos
Autores principales: Singleton, Dean C., Rouhi, Pegah, Zois, Christos E., Haider, Syed, Li, Ji-Liang, Kessler, Benedikt M., Cao, Yihai, Harris, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430306/
https://www.ncbi.nlm.nih.gov/pubmed/25486436
http://dx.doi.org/10.1038/onc.2014.396

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