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Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis
Hypoxia is a common feature of locally advanced breast cancers and is associated with increased metastasis and poorer survival. Stabilisation of Hypoxia-Inducible Factor-1α (HIF1α) in tumours causes transcriptional changes in numerous genes that function at distinct stages of the metastatic cascade....
Autores principales: | Singleton, Dean C., Rouhi, Pegah, Zois, Christos E., Haider, Syed, Li, Ji-Liang, Kessler, Benedikt M., Cao, Yihai, Harris, Adrian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430306/ https://www.ncbi.nlm.nih.gov/pubmed/25486436 http://dx.doi.org/10.1038/onc.2014.396 |
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