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A new antibiotic with potent activity targets MscL

The growing problem of antibiotic-resistant bacteria is a major threat to human health. Paradoxically, new antibiotic discovery is declining, with most of the recently approved antibiotics corresponding to new uses for old antibiotics or structurally similar derivatives of known antibiotics. We used...

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Detalles Bibliográficos
Autores principales: Iscla, Irene, Wray, Robin, Blount, Paul, Larkins-Ford, Jonah, Conery, Annie L, Ausubel, Frederick M, Ramu, Soumya, Kavanagh, Angela, Huang, Johnny X, Blaskovich, Mark A, Cooper, Matthew A, Obregon-Henao, Andres, Orme, Ian, Tjandra, Edwin S, Stroeher, Uwe H, Brown, Melissa H, Macardle, Cindy, van Holst, Nick, Ling Tong, Chee, Slattery, Ashley D, Gibson, Christopher T, Raston, Colin L, Boulos, Ramiz A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430313/
https://www.ncbi.nlm.nih.gov/pubmed/25649856
http://dx.doi.org/10.1038/ja.2015.4