Cargando…

FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

The ubiquitin-proteasome system for protein degradation plays a major role in regulating cell function and many signaling proteins are tightly controlled by this mechanism. Among these, Regulator of G Protein Signaling 2 (RGS2) is a target for rapid proteasomal degradation, however, the specific enz...

Descripción completa

Detalles Bibliográficos
Autores principales: Sjögren, Benita, Swaney, Steven, Neubig, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430315/
https://www.ncbi.nlm.nih.gov/pubmed/25970626
http://dx.doi.org/10.1371/journal.pone.0123581

Ejemplares similares