The tryptophan-derived endogenous arylhydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole (FICZ) is a nanomolar UVA-photosensitizer in epidermal keratinocytes

Endogenous UVA-chromophores may act as sensitizers of oxidative stress underlying cutaneous photoaging and photocarcinogenesis, but the molecular identity of non-DNA key chromophores displaying UVA-driven photodyamic activity in human skin remains largely undefined. Here we report that 6-formylindol...

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Detalles Bibliográficos
Autores principales: Park, Sophia L., Justiniano, Rebecca, Williams, Joshua D., Cabello, Christopher M., Qiao, Shuxi, Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430374/
https://www.ncbi.nlm.nih.gov/pubmed/25431849
http://dx.doi.org/10.1038/jid.2014.503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430374/
https://www.ncbi.nlm.nih.gov/pubmed/25431849
http://dx.doi.org/10.1038/jid.2014.503

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