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The tryptophan-derived endogenous arylhydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole (FICZ) is a nanomolar UVA-photosensitizer in epidermal keratinocytes
Endogenous UVA-chromophores may act as sensitizers of oxidative stress underlying cutaneous photoaging and photocarcinogenesis, but the molecular identity of non-DNA key chromophores displaying UVA-driven photodyamic activity in human skin remains largely undefined. Here we report that 6-formylindol...
Autores principales: | Park, Sophia L., Justiniano, Rebecca, Williams, Joshua D., Cabello, Christopher M., Qiao, Shuxi, Wondrak, Georg T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430374/ https://www.ncbi.nlm.nih.gov/pubmed/25431849 http://dx.doi.org/10.1038/jid.2014.503 |
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