14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization

The homozygous repeated epilation (Er/Er) mouse mutant of the gene encoding 14-3-3σ displays an epidermal phenotype characterized by hyperproliferative keratinocytes and undifferentiated epidermis. Heterozygous Er/+ mice develop spontaneous skin tumors and are highly sensitive to tumor-promoting DMB...

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Detalles Bibliográficos
Autores principales: Sambandam, Sumitha A.T., Kasetti, Ramesh Babu, Xue, Lei, Dean, Douglas C., Lu, Qingxian, Li, Qiutang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430425/
https://www.ncbi.nlm.nih.gov/pubmed/25668240
http://dx.doi.org/10.1038/jid.2015.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430425/
https://www.ncbi.nlm.nih.gov/pubmed/25668240
http://dx.doi.org/10.1038/jid.2015.42

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