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14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization
The homozygous repeated epilation (Er/Er) mouse mutant of the gene encoding 14-3-3σ displays an epidermal phenotype characterized by hyperproliferative keratinocytes and undifferentiated epidermis. Heterozygous Er/+ mice develop spontaneous skin tumors and are highly sensitive to tumor-promoting DMB...
Autores principales: | Sambandam, Sumitha A.T., Kasetti, Ramesh Babu, Xue, Lei, Dean, Douglas C., Lu, Qingxian, Li, Qiutang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430425/ https://www.ncbi.nlm.nih.gov/pubmed/25668240 http://dx.doi.org/10.1038/jid.2015.42 |
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