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Inbreeding among Caribbean Hispanics from the Dominican Republic and the Effects on the Risk of Alzheimer's Disease
BACKGROUND: Inbreeding can be associated with a modification in disease risk due to excess homozygosity of recessive alleles impacting a wide range of phenotypes. We estimated the inbreeding coefficient in Caribbean Hispanics and examined its effects on risk of late-onset Alzheimer's Disease (L...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430451/ https://www.ncbi.nlm.nih.gov/pubmed/25394174 http://dx.doi.org/10.1038/gim.2014.161 |