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Spindle assembly checkpoint is sufficient for complete Cdc20 sequestering in mitotic control

The spindle checkpoint assembly (SAC) ensures genome fidelity by temporarily delaying anaphase onset, until all chromosomes are properly attached to the mitotic spindle. The SAC delays mitotic progression by preventing activation of the ubiquitin ligase anaphase-promoting complex (APC/C) or cyclosom...

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Detalles Bibliográficos
Autor principal:	Ibrahim, Bashar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430708/ https://www.ncbi.nlm.nih.gov/pubmed/25977749 http://dx.doi.org/10.1016/j.csbj.2015.03.006

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