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Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction

High levels of oxygen (hyperoxia) are often used to treat individuals with respiratory distress, yet prolonged hyperoxia causes mitochondrial dysfunction and excessive reactive oxygen species (ROS) that can damage molecules such as DNA. Ataxia telangiectasia mutated (ATM) kinase is activated by nucl...

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Detalles Bibliográficos
Autores principales:	Resseguie, Emily A., Staversky, Rhonda J., Brookes, Paul S., O’Reilly, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430709/ https://www.ncbi.nlm.nih.gov/pubmed/25967673 http://dx.doi.org/10.1016/j.redox.2015.04.012

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