Mechanism study of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR by iTRAQ-based proteomic analysis

BACKGROUND: Multidrug resistance (MDR) is a major obstacle to the treatment of gastric cancer (GC). Using a phage display approach, we previously obtained the peptide GMBP1, which specifically binds to the surface of MDR gastric cancer cells and is subsequently internalized. Furthermore, GMBP1 was s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojuan, Li, Yani, Xu, Guanghui, Liu, Muhan, Xue, Lin, Liu, Lijuan, Hu, Sijun, Zhang, Ying, Nie, Yongzhan, Liang, Shuhui, Wang, Biaoluo, Ding, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430905/
https://www.ncbi.nlm.nih.gov/pubmed/25943993
http://dx.doi.org/10.1186/s12885-015-1361-3

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