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Performance of a blockwise approach in variable selection using linkage disequilibrium information
BACKGROUND: Genome-wide association studies (GWAS) aim at finding genetic markers that are significantly associated with a phenotype of interest. Single nucleotide polymorphism (SNP) data from the entire genome are collected for many thousands of SNP markers, leading to high-dimensional regression p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430909/ https://www.ncbi.nlm.nih.gov/pubmed/25951947 http://dx.doi.org/10.1186/s12859-015-0556-6 |