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Epigenetic reprogramming of melanoma cells by vitamin C treatment

BACKGROUND: The loss of 5-hydroxymethylcytosine (5hmC) has been identified as a novel epigenetic hallmark for melanoma. One of the known mechanisms underlying the loss of 5hmC is the decrease in expression of ten-eleven translocation family dioxygenase (TET) genes, which encode enzymes that catalyze...

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Detalles Bibliográficos
Autores principales:	Gustafson, Christopher B, Yang, Cuixia, Dickson, Kevin M, Shao, Hongwei, Van Booven, Derek, Harbour, J William, Liu, Zhao-Jun, Wang, Gaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430922/ https://www.ncbi.nlm.nih.gov/pubmed/25977731 http://dx.doi.org/10.1186/s13148-015-0087-z

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