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Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria
BACKGROUND: Small Rho-GTPases are critical mediators of neuronal plasticity and are involved in the pathogenesis of several psychiatric and neurological disorders. Rac-GTPase forms a multiprotein complex with upstream and downstream regulators that are essential for the spatiotemporal transmission o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430930/ https://www.ncbi.nlm.nih.gov/pubmed/25924612 http://dx.doi.org/10.1186/s12858-015-0040-y |