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Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis

INTRODUCTION: Impairment in the ability of the inflamed synovium to generate cortisol has been proposed to be a factor in the persistence and severity of inflammatory arthritis. In the inflamed synovium, cortisol is generated from cortisone by the 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) e...

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Detalles Bibliográficos
Autores principales:	Nanus, Dominika E, Filer, Andrew D, Yeo, Lorraine, Scheel-Toellner, Dagmar, Hardy, Rowan, Lavery, Gareth G, Stewart, Paul M, Buckley, Christopher D, Tomlinson, Jeremy W, Cooper, Mark S, Raza, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431033/ https://www.ncbi.nlm.nih.gov/pubmed/25971255 http://dx.doi.org/10.1186/s13075-015-0633-2

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