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Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring

Electronic devices based on organic thin-film transistors (OTFT) have the potential to supply the demand for portable and low-cost gadgets, mainly as sensors for in situ disease diagnosis and environment monitoring. For that reason, poly(3-hexylthiophene) (P3HT) as the active layer in the widely-use...

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Autores principales: Cavallari, Marco R., Izquierdo, José E. E., Braga, Guilherme S., Dirani, Ely A. T., Pereira-da-Silva, Marcelo A., Rodríguez, Estrella F. G., Fonseca, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431216/
https://www.ncbi.nlm.nih.gov/pubmed/25912354
http://dx.doi.org/10.3390/s150409592
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author Cavallari, Marco R.
Izquierdo, José E. E.
Braga, Guilherme S.
Dirani, Ely A. T.
Pereira-da-Silva, Marcelo A.
Rodríguez, Estrella F. G.
Fonseca, Fernando J.
author_facet Cavallari, Marco R.
Izquierdo, José E. E.
Braga, Guilherme S.
Dirani, Ely A. T.
Pereira-da-Silva, Marcelo A.
Rodríguez, Estrella F. G.
Fonseca, Fernando J.
author_sort Cavallari, Marco R.
collection PubMed
description Electronic devices based on organic thin-film transistors (OTFT) have the potential to supply the demand for portable and low-cost gadgets, mainly as sensors for in situ disease diagnosis and environment monitoring. For that reason, poly(3-hexylthiophene) (P3HT) as the active layer in the widely-used bottom-gate/bottom-contact OTFT structure was deposited over highly-doped silicon substrates covered with thermally-grown oxide to detect vapor-phase compounds. A ten-fold organochloride and ammonia sensitivity compared to bare sensors corroborated the application of this semiconducting polymer in sensors. Furthermore, P3HT TFTs presented approximately three-order higher normalized sensitivity than any chemical sensor addressed herein. The results demonstrate that while TFTs respond linearly at the lowest concentration values herein, chemical sensors present such an operating regime mostly above 2000 ppm. Simultaneous alteration of charge carrier mobility and threshold voltage is responsible for pushing the detection limit down to units of ppm of ammonia, as well as tens of ppm of alcohol or ketones. Nevertheless, P3HT transistors and chemical sensors could compose an electronic nose operated at room temperature for a wide range concentration evaluation (1–10,000 ppm) of gaseous analytes. Targeted analytes include not only biomarkers for diseases, such as uremia, cirrhosis, lung cancer and diabetes, but also gases for environment monitoring in food, cosmetic and microelectronics industries.
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spelling pubmed-44312162015-05-19 Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring Cavallari, Marco R. Izquierdo, José E. E. Braga, Guilherme S. Dirani, Ely A. T. Pereira-da-Silva, Marcelo A. Rodríguez, Estrella F. G. Fonseca, Fernando J. Sensors (Basel) Article Electronic devices based on organic thin-film transistors (OTFT) have the potential to supply the demand for portable and low-cost gadgets, mainly as sensors for in situ disease diagnosis and environment monitoring. For that reason, poly(3-hexylthiophene) (P3HT) as the active layer in the widely-used bottom-gate/bottom-contact OTFT structure was deposited over highly-doped silicon substrates covered with thermally-grown oxide to detect vapor-phase compounds. A ten-fold organochloride and ammonia sensitivity compared to bare sensors corroborated the application of this semiconducting polymer in sensors. Furthermore, P3HT TFTs presented approximately three-order higher normalized sensitivity than any chemical sensor addressed herein. The results demonstrate that while TFTs respond linearly at the lowest concentration values herein, chemical sensors present such an operating regime mostly above 2000 ppm. Simultaneous alteration of charge carrier mobility and threshold voltage is responsible for pushing the detection limit down to units of ppm of ammonia, as well as tens of ppm of alcohol or ketones. Nevertheless, P3HT transistors and chemical sensors could compose an electronic nose operated at room temperature for a wide range concentration evaluation (1–10,000 ppm) of gaseous analytes. Targeted analytes include not only biomarkers for diseases, such as uremia, cirrhosis, lung cancer and diabetes, but also gases for environment monitoring in food, cosmetic and microelectronics industries. MDPI 2015-04-22 /pmc/articles/PMC4431216/ /pubmed/25912354 http://dx.doi.org/10.3390/s150409592 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cavallari, Marco R.
Izquierdo, José E. E.
Braga, Guilherme S.
Dirani, Ely A. T.
Pereira-da-Silva, Marcelo A.
Rodríguez, Estrella F. G.
Fonseca, Fernando J.
Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title_full Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title_fullStr Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title_full_unstemmed Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title_short Enhanced Sensitivity of Gas Sensor Based on Poly(3-hexylthiophene) Thin-Film Transistors for Disease Diagnosis and Environment Monitoring
title_sort enhanced sensitivity of gas sensor based on poly(3-hexylthiophene) thin-film transistors for disease diagnosis and environment monitoring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431216/
https://www.ncbi.nlm.nih.gov/pubmed/25912354
http://dx.doi.org/10.3390/s150409592
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