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Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial
OBJECTIVE: CONCERTO was a randomised, double-blind, parallel-armed study of methotrexate (MTX) in combination with adalimumab to assess whether an increasing trend of efficacy and decreased safety exists when increasing MTX dose in patients with early rheumatoid arthritis (RA). METHODS: Early, biolo...
Autores principales: | Burmester, Gerd-Rűdiger, Kivitz, Alan J, Kupper, Hartmut, Arulmani, Udayasankar, Florentinus, Stefan, Goss, Sandra L, Rathmann, Suchitrita S, Fleischmann, Roy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431334/ https://www.ncbi.nlm.nih.gov/pubmed/24550168 http://dx.doi.org/10.1136/annrheumdis-2013-204769 |
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