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Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer

Although mammalian cloning by somatic cell nuclear transfer (SCNT) has been established in various species, the low developmental efficiency has hampered its practical applications. Treatment of SCNT-derived embryos with histone deacetylase (HDAC) inhibitors can improve their development, but the un...

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Detalles Bibliográficos
Autores principales: Inoue, Kimiko, Oikawa, Mami, Kamimura, Satoshi, Ogonuki, Narumi, Nakamura, Toshinobu, Nakano, Toru, Abe, Kuniya, Ogura, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431350/
https://www.ncbi.nlm.nih.gov/pubmed/25974394
http://dx.doi.org/10.1038/srep10127