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Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer
Although mammalian cloning by somatic cell nuclear transfer (SCNT) has been established in various species, the low developmental efficiency has hampered its practical applications. Treatment of SCNT-derived embryos with histone deacetylase (HDAC) inhibitors can improve their development, but the un...
Autores principales: | Inoue, Kimiko, Oikawa, Mami, Kamimura, Satoshi, Ogonuki, Narumi, Nakamura, Toshinobu, Nakano, Toru, Abe, Kuniya, Ogura, Atsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431350/ https://www.ncbi.nlm.nih.gov/pubmed/25974394 http://dx.doi.org/10.1038/srep10127 |
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