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Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster
Appropriate and robust behavioral control in a noisy environment is important for the survival of most organisms. Understanding such robust behavioral control has been an attractive subject in neuroscience research. Here, we investigated the processing of wide-field motion with random dot noise at b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431354/ https://www.ncbi.nlm.nih.gov/pubmed/25974721 http://dx.doi.org/10.1038/srep10253 |
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author | Suzuki, Yoshinori Ikeda, Hideaki Miyamoto, Takuya Miyakawa, Hiroyoshi Seki, Yoichi Aonishi, Toru Morimoto, Takako |
author_facet | Suzuki, Yoshinori Ikeda, Hideaki Miyamoto, Takuya Miyakawa, Hiroyoshi Seki, Yoichi Aonishi, Toru Morimoto, Takako |
author_sort | Suzuki, Yoshinori |
collection | PubMed |
description | Appropriate and robust behavioral control in a noisy environment is important for the survival of most organisms. Understanding such robust behavioral control has been an attractive subject in neuroscience research. Here, we investigated the processing of wide-field motion with random dot noise at both the behavioral and neuronal level in Drosophila melanogaster. We measured the head yaw optomotor response (OMR) and the activity of motion-sensitive neurons, horizontal system (HS) cells, with in vivo whole-cell patch clamp recordings at various levels of noise intensity. We found that flies had a robust sensation of motion direction under noisy conditions, while membrane potential changes of HS cells were not correlated with behavioral responses. By applying signal classification theory to the distributions of HS cell responses, however, we found that motion direction under noise can be clearly discriminated by HS cells, and that this discrimination performance was quantitatively similar to that of OMR. Furthermore, we successfully reproduced HS cell activity in response to noisy motion stimuli with a local motion detector model including a spatial filter and threshold function. This study provides evidence for the physiological basis of noise-robust behavior in a tiny insect brain. |
format | Online Article Text |
id | pubmed-4431354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-44313542015-05-22 Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster Suzuki, Yoshinori Ikeda, Hideaki Miyamoto, Takuya Miyakawa, Hiroyoshi Seki, Yoichi Aonishi, Toru Morimoto, Takako Sci Rep Article Appropriate and robust behavioral control in a noisy environment is important for the survival of most organisms. Understanding such robust behavioral control has been an attractive subject in neuroscience research. Here, we investigated the processing of wide-field motion with random dot noise at both the behavioral and neuronal level in Drosophila melanogaster. We measured the head yaw optomotor response (OMR) and the activity of motion-sensitive neurons, horizontal system (HS) cells, with in vivo whole-cell patch clamp recordings at various levels of noise intensity. We found that flies had a robust sensation of motion direction under noisy conditions, while membrane potential changes of HS cells were not correlated with behavioral responses. By applying signal classification theory to the distributions of HS cell responses, however, we found that motion direction under noise can be clearly discriminated by HS cells, and that this discrimination performance was quantitatively similar to that of OMR. Furthermore, we successfully reproduced HS cell activity in response to noisy motion stimuli with a local motion detector model including a spatial filter and threshold function. This study provides evidence for the physiological basis of noise-robust behavior in a tiny insect brain. Nature Publishing Group 2015-05-14 /pmc/articles/PMC4431354/ /pubmed/25974721 http://dx.doi.org/10.1038/srep10253 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Suzuki, Yoshinori Ikeda, Hideaki Miyamoto, Takuya Miyakawa, Hiroyoshi Seki, Yoichi Aonishi, Toru Morimoto, Takako Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title | Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title_full | Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title_fullStr | Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title_full_unstemmed | Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title_short | Noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in Drosophila melanogaster |
title_sort | noise-robust recognition of wide-field motion direction and the underlying neural mechanisms in drosophila melanogaster |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431354/ https://www.ncbi.nlm.nih.gov/pubmed/25974721 http://dx.doi.org/10.1038/srep10253 |
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