Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620

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The aim of the present study was to examine the role of protease-activated receptor-1 (PAR1)-stimulated platelet activation in the epithelial-mesenchymal transition (EMT) and migration of colon cancer cells, and to identify the underlying mechanisms. TFLLR-NH(2), a PAR1 agonist, was used to activate...

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Detalles Bibliográficos
Autores principales: JIA, YITAO, ZHANG, SUQIAO, MIAO, LINGLING, WANG, JINGBAO, JIN, ZUJIAN, GU, BIN, DUAN, ZHIHUI, ZHAO, ZHAOLONG, MA, SHUNMAO, ZHANG, WENJIN, LI, ZHONGXIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431448/
https://www.ncbi.nlm.nih.gov/pubmed/25846512
http://dx.doi.org/10.3892/or.2015.3897
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