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Conformational Study of an Artificial Metal-Dependent Regulation Site for Use in Designer Proteins

This report describes the dimerisation of glutathione, and by extension, other cysteine-containing peptides or protein fragments, with a 5, 5’-disubstituted-2, 2’-bipyridine or 6, 6”-disubstituted-2, 2’:6’,2”-terpyridine unit. The resulting bipy-GS(2) and terpy-GS(2) were investigated as potential m...

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Detalles Bibliográficos
Autores principales: Oheix, Emmanuel, Spencer, Neil, Gethings, Lee A, Peacock, Anna F A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431501/
https://www.ncbi.nlm.nih.gov/pubmed/25995524
http://dx.doi.org/10.1002/zaac.201300131