TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases

BACKGROUND: TP53 mutation is more prevalent in therapy-related myeloid neoplasms (t-MN) than their de novo counterparts; however, the pattern of mutations involving TP53 gene in t-MN versus de novo diseases is largely unknown. METHODS: We collected 108 consecutive patients with therapy-related myelo...

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Detalles Bibliográficos
Autores principales: Ok, Chi Young, Patel, Keyur P, Garcia-Manero, Guillermo, Routbort, Mark J, Peng, Jie, Tang, Guilin, Goswami, Maitrayee, Young, Ken H, Singh, Rajesh, Medeiros, L Jeffrey, Kantarjian, Hagop M, Luthra, Rajyalakshmi, Wang, Sa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431603/
https://www.ncbi.nlm.nih.gov/pubmed/25952993
http://dx.doi.org/10.1186/s13045-015-0139-z

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