Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells

In an mRNA profiling screen performed to unveil novel mechanisms of leukemogenesis, we found that the sentrin-specific protease 5 (SENP5) was significantly repressed in clinical acute myeloid leukemia when compared to healthy neutrophil samples. SENP5 is an enzyme that targets and cleaves small ubiq...

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Detalles Bibliográficos
Autores principales: Federzoni, Elena A., Gloor, Severin, Jin, Jing, Shan-Krauer, Deborah, Fey, Martin F., Torbett, Bruce E., Tschan, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431638/
https://www.ncbi.nlm.nih.gov/pubmed/25984443
http://dx.doi.org/10.1016/j.lrr.2015.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431638/
https://www.ncbi.nlm.nih.gov/pubmed/25984443
http://dx.doi.org/10.1016/j.lrr.2015.04.002

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