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Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells
In an mRNA profiling screen performed to unveil novel mechanisms of leukemogenesis, we found that the sentrin-specific protease 5 (SENP5) was significantly repressed in clinical acute myeloid leukemia when compared to healthy neutrophil samples. SENP5 is an enzyme that targets and cleaves small ubiq...
Autores principales: | Federzoni, Elena A., Gloor, Severin, Jin, Jing, Shan-Krauer, Deborah, Fey, Martin F., Torbett, Bruce E., Tschan, Mario P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431638/ https://www.ncbi.nlm.nih.gov/pubmed/25984443 http://dx.doi.org/10.1016/j.lrr.2015.04.002 |
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