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Combined enzyme/prodrug treatment by genetically engineered AT-MSC exerts synergy and inhibits growth of MDA-MB-231 induced lung metastases

BACKGROUND: Metastatic spread of tumor cells remains a serious problem in cancer treatment. Gene-directed enzyme/prodrug therapy mediated by tumor-homing genetically engineered mesenchymal stromal cells (MSC) represents a promising therapeutic modality for elimination of disseminated cells. Efficacy...

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Detalles Bibliográficos
Autores principales:	Matuskova, Miroslava, Kozovska, Zuzana, Toro, Lenka, Durinikova, Erika, Tyciakova, Silvia, Cierna, Zuzana, Bohovic, Roman, Kucerova, Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431639/ https://www.ncbi.nlm.nih.gov/pubmed/25884597 http://dx.doi.org/10.1186/s13046-015-0149-2

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