Acidosis Sensing Receptor GPR65 Correlates with Anti-Apoptotic Bcl-2 Family Member Expression in CLL Cells: Potential Implications for the CLL Microenvironment

The tumor microenvironment is generally an acidic environment, yet the effect of extracellular acidosis on chronic lymphocytic leukemia (CLL) is not well established. Here we are the first to report that the extracellular acid sensing G-protein coupled receptor, GPR65, is expressed in primary CLL ce...

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Detalles Bibliográficos
Autores principales: Rosko, Ashley E, McColl, Karen S, Zhong, Fei, Ryder, Christopher B, Chang, Ming-Jin, Sattar, Abdus, Caimi, Paolo F, Hill, Brian T, Al-Harbi, Sayer, Almasan, Alexandru, Distelhorst, Clark W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431653/
https://www.ncbi.nlm.nih.gov/pubmed/25984552
http://dx.doi.org/10.4172/2329-6917.1000160

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