Specific Genomic Aberrations Predict Survival, But Low Mutation Rate in Cancer Hot Spots, in Clear Cell Renal Cell Carcinoma

Detailed genetic profiling of clear cell renal cell carcinoma (ccRCC) has revealed genomic regions commonly affected by structural changes and a general genetic heterogeneity. VHL and PBRM1, both located at chromosome 3p, are 2 major genes mutated at high frequency but apart from these aberrations,...

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Detalles Bibliográficos
Autores principales: Köhn, Linda, Svenson, Ulrika, Ljungberg, Börje, Roos, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431677/
https://www.ncbi.nlm.nih.gov/pubmed/24992170
http://dx.doi.org/10.1097/PAI.0000000000000087

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