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Toll-Like Receptor 9 Signaling Regulates Tissue Factor and Tissue Factor Pathway Inhibitor Expression in Human Endothelial Cells and Coagulation in Mice

OBJECTIVE: Bacterial DNA (CpG DNA) persists in tissues and blood under pathological conditions that are associated with enhanced intravascular coagulation. Toll-like receptor 9 recognizes CpG DNA and elicits innate and adoptive immunity, yet the impact of CpG DNA on coagulation has not been studied....

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Detalles Bibliográficos
Autores principales:	El Kebir, Driss, Damlaj, Anas, Makhezer, Nesrine, Filep, János G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2015
Materias:	Online Laboratory Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431678/ https://www.ncbi.nlm.nih.gov/pubmed/25855902 http://dx.doi.org/10.1097/CCM.0000000000001005

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