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The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex, systemic autoimmune disease with a diverse range of immunological and clinical manifestations. The introduction of broad spectrum immunosuppressive therapies and better management of acute disease exacerbations have improved outcomes for lupus patient...
Autores principales: | Liu, Yuan, Ye, Josephine, Shin Ogawa, Luisa, Inoue, Takayo, Huang, Qin, Chu, John, Bates, Richard C., Ying, Weiwen, Sonderfan, Andrew J., Rao, Patricia E., Zhou, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431681/ https://www.ncbi.nlm.nih.gov/pubmed/25974040 http://dx.doi.org/10.1371/journal.pone.0127361 |
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