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Forecasting the 2013–2014 Influenza Season Using Wikipedia

Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and Prevention (CDC), seasonal influenza affects 5% to 20% of the U.S. po...

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Autores principales: Hickmann, Kyle S., Fairchild, Geoffrey, Priedhorsky, Reid, Generous, Nicholas, Hyman, James M., Deshpande, Alina, Del Valle, Sara Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431683/
https://www.ncbi.nlm.nih.gov/pubmed/25974758
http://dx.doi.org/10.1371/journal.pcbi.1004239
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author Hickmann, Kyle S.
Fairchild, Geoffrey
Priedhorsky, Reid
Generous, Nicholas
Hyman, James M.
Deshpande, Alina
Del Valle, Sara Y.
author_facet Hickmann, Kyle S.
Fairchild, Geoffrey
Priedhorsky, Reid
Generous, Nicholas
Hyman, James M.
Deshpande, Alina
Del Valle, Sara Y.
author_sort Hickmann, Kyle S.
collection PubMed
description Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and Prevention (CDC), seasonal influenza affects 5% to 20% of the U.S. population and causes major economic impacts resulting from hospitalization and absenteeism. Understanding influenza dynamics and forecasting its impact is fundamental for developing prevention and mitigation strategies. We combine modern data assimilation methods with Wikipedia access logs and CDC influenza-like illness (ILI) reports to create a weekly forecast for seasonal influenza. The methods are applied to the 2013-2014 influenza season but are sufficiently general to forecast any disease outbreak, given incidence or case count data. We adjust the initialization and parametrization of a disease model and show that this allows us to determine systematic model bias. In addition, we provide a way to determine where the model diverges from observation and evaluate forecast accuracy. Wikipedia article access logs are shown to be highly correlated with historical ILI records and allow for accurate prediction of ILI data several weeks before it becomes available. The results show that prior to the peak of the flu season, our forecasting method produced 50% and 95% credible intervals for the 2013-2014 ILI observations that contained the actual observations for most weeks in the forecast. However, since our model does not account for re-infection or multiple strains of influenza, the tail of the epidemic is not predicted well after the peak of flu season has passed.
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spelling pubmed-44316832015-05-27 Forecasting the 2013–2014 Influenza Season Using Wikipedia Hickmann, Kyle S. Fairchild, Geoffrey Priedhorsky, Reid Generous, Nicholas Hyman, James M. Deshpande, Alina Del Valle, Sara Y. PLoS Comput Biol Research Article Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and Prevention (CDC), seasonal influenza affects 5% to 20% of the U.S. population and causes major economic impacts resulting from hospitalization and absenteeism. Understanding influenza dynamics and forecasting its impact is fundamental for developing prevention and mitigation strategies. We combine modern data assimilation methods with Wikipedia access logs and CDC influenza-like illness (ILI) reports to create a weekly forecast for seasonal influenza. The methods are applied to the 2013-2014 influenza season but are sufficiently general to forecast any disease outbreak, given incidence or case count data. We adjust the initialization and parametrization of a disease model and show that this allows us to determine systematic model bias. In addition, we provide a way to determine where the model diverges from observation and evaluate forecast accuracy. Wikipedia article access logs are shown to be highly correlated with historical ILI records and allow for accurate prediction of ILI data several weeks before it becomes available. The results show that prior to the peak of the flu season, our forecasting method produced 50% and 95% credible intervals for the 2013-2014 ILI observations that contained the actual observations for most weeks in the forecast. However, since our model does not account for re-infection or multiple strains of influenza, the tail of the epidemic is not predicted well after the peak of flu season has passed. Public Library of Science 2015-05-14 /pmc/articles/PMC4431683/ /pubmed/25974758 http://dx.doi.org/10.1371/journal.pcbi.1004239 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Research Article
Hickmann, Kyle S.
Fairchild, Geoffrey
Priedhorsky, Reid
Generous, Nicholas
Hyman, James M.
Deshpande, Alina
Del Valle, Sara Y.
Forecasting the 2013–2014 Influenza Season Using Wikipedia
title Forecasting the 2013–2014 Influenza Season Using Wikipedia
title_full Forecasting the 2013–2014 Influenza Season Using Wikipedia
title_fullStr Forecasting the 2013–2014 Influenza Season Using Wikipedia
title_full_unstemmed Forecasting the 2013–2014 Influenza Season Using Wikipedia
title_short Forecasting the 2013–2014 Influenza Season Using Wikipedia
title_sort forecasting the 2013–2014 influenza season using wikipedia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431683/
https://www.ncbi.nlm.nih.gov/pubmed/25974758
http://dx.doi.org/10.1371/journal.pcbi.1004239
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