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Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1

The myeloid translocation gene 16 (MTG16) co-repressor down regulates expression of multiple glycolytic genes, which are targets of the hypoxia-inducible factor 1 (HIF1) heterodimer transcription factor that is composed of oxygen-regulated labile HIF1α and stable HIF1β subunits. For this reason, we...

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Detalles Bibliográficos
Autores principales: Kumar, Parveen, Gullberg, Urban, Olsson, Inge, Ajore, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431712/
https://www.ncbi.nlm.nih.gov/pubmed/25974097
http://dx.doi.org/10.1371/journal.pone.0123725