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Mechanisms of Stage-Transcending Protection Following Immunization of Mice with Late Liver Stage-Arresting Genetically Attenuated Malaria Parasites
Malaria, caused by Plasmodium parasite infection, continues to be one of the leading causes of worldwide morbidity and mortality. Development of an effective vaccine has been encumbered by the complex life cycle of the parasite that has distinct pre-erythrocytic and erythrocytic stages of infection...
Autores principales: | Sack, Brandon K., Keitany, Gladys J., Vaughan, Ashley M., Miller, Jessica L., Wang, Ruobing, Kappe, Stefan H. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431720/ https://www.ncbi.nlm.nih.gov/pubmed/25974076 http://dx.doi.org/10.1371/journal.ppat.1004855 |
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