Co-Evolution of Somatic Variation in Primary and Metastatic Colorectal Cancer May Expand Biopsy Indications in the Molecular Era

INTRODUCTION: Metastasis is thought to be a clonal event whereby a single cell initiates the development of a new tumor at a distant site. However the degree to which primary and metastatic tumors differ on a molecular level remains unclear. To further evaluate these concepts, we used next generatio...

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Detalles Bibliográficos
Autores principales: Kim, Richard, Schell, Michael J., Teer, Jamie K., Greenawalt, Danielle M., Yang, Mingli, Yeatman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431733/
https://www.ncbi.nlm.nih.gov/pubmed/25974029
http://dx.doi.org/10.1371/journal.pone.0126670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431733/
https://www.ncbi.nlm.nih.gov/pubmed/25974029
http://dx.doi.org/10.1371/journal.pone.0126670

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