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Diacylglycerol O-Acyltransferase Type-1 Synthesizes Retinyl Esters in the Retina and Retinal Pigment Epithelium
Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment epithelium (RPE). The major retinyl-ester synthase in RPE cells is lecithin:retinol acyl-transferase (LRAT). A second palmitoyl coenzyme A-dependent r...
Autores principales: | Kaylor, Joanna J., Radu, Roxana A., Bischoff, Nicholas, Makshanoff, Jacob, Hu, Jane, Lloyd, Marcia, Eddington, Shannan, Bianconi, Tran, Bok, Dean, Travis, Gabriel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431840/ https://www.ncbi.nlm.nih.gov/pubmed/25974161 http://dx.doi.org/10.1371/journal.pone.0125921 |
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