Identification of Disease-Promoting HLA Class I and Protective Class II Modifiers in Japanese Patients with Familial Mediterranean Fever

OBJECTIVES: The genotype-phenotype correlation of MEFV remains unclear for the familial Mediterranean fever (FMF) patients, especially without canonical MEFV mutations in exon 10. The risk of FMF appeared to be under the influence of other factors in this case. The contribution of HLA polymorphisms...

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Detalles Bibliográficos
Autores principales: Yasunami, Michio, Nakamura, Hitomi, Agematsu, Kazunaga, Nakamura, Akinori, Yazaki, Masahide, Kishida, Dai, Yachie, Akihiro, Toma, Tomoko, Masumoto, Junya, Ida, Hiroaki, Koga, Tomohiro, Kawakami, Atsushi, Eguchi, Katsumi, Furukawa, Hiroshi, Nakamura, Tadashi, Nakamura, Minoru, Migita, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431852/
https://www.ncbi.nlm.nih.gov/pubmed/25974247
http://dx.doi.org/10.1371/journal.pone.0125938

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