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Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche

We previously reported a new approach for culturing difficult-to-preserve primary patient-derived multiple myeloma cells (MMC) using an osteoblast (OSB)-derived 3D tissue scaffold constructed in a perfused microfluidic environment and a culture medium supplemented with patient plasma. In the current...

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Detalles Bibliográficos
Autores principales: Zhang, Wenting, Gu, Yexin, Sun, Qiaoling, Siegel, David S., Tolias, Peter, Yang, Zheng, Lee, Woo Y., Zilberberg, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431864/
https://www.ncbi.nlm.nih.gov/pubmed/25973790
http://dx.doi.org/10.1371/journal.pone.0125995