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Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche
We previously reported a new approach for culturing difficult-to-preserve primary patient-derived multiple myeloma cells (MMC) using an osteoblast (OSB)-derived 3D tissue scaffold constructed in a perfused microfluidic environment and a culture medium supplemented with patient plasma. In the current...
Autores principales: | Zhang, Wenting, Gu, Yexin, Sun, Qiaoling, Siegel, David S., Tolias, Peter, Yang, Zheng, Lee, Woo Y., Zilberberg, Jenny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431864/ https://www.ncbi.nlm.nih.gov/pubmed/25973790 http://dx.doi.org/10.1371/journal.pone.0125995 |
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