Ensemble Force Changes that Result from Human Cardiac Myosin Mutations and a Small-Molecule Effector

Cardiomyopathies due to mutations in human β-cardiac myosin are a significant cause of heart failure, sudden death, and arrhythmia. To understand the underlying molecular basis of changes in the contractile system’s force production due to such mutations and search for potential drugs that restore f...

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Detalles Bibliográficos
Autores principales: Aksel, Tural, Yu, Elizabeth Choe, Sutton, Shirley, Ruppel, Kathleen M., Spudich, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431957/
https://www.ncbi.nlm.nih.gov/pubmed/25937279
http://dx.doi.org/10.1016/j.celrep.2015.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431957/
https://www.ncbi.nlm.nih.gov/pubmed/25937279
http://dx.doi.org/10.1016/j.celrep.2015.04.006

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