Cargando…

Adding Erlotinib to Chemoradiation Improves Overall Survival but not Progression-Free Survival in Stage III Non-Small-Cell Lung Cancer

BACKGROUND: Concurrent chemoradiotherapy is the standard of care for inoperable stage III non-small cell lung cancer (NSCLC) for patients who can tolerate it. We explored if adding erlotinib would increase the effectiveness of chemoradiotherapy without increasing toxicity in a single-arm prospective...

Descripción completa

Detalles Bibliográficos
Autores principales:	Komaki, Ritsuko, Allen, Pamela K., Wei, Xiong, Blumenschein, George R., Tang, Ximing, Lee, J. Jack, Welsh, James W., Wistuba, Ignacio I., Liu, Diane D., Hong, Waun Ki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432249/ https://www.ncbi.nlm.nih.gov/pubmed/25968826 http://dx.doi.org/10.1016/j.ijrobp.2015.02.005

Ejemplares similares

CD24 and Nanog expression in Stem Cells in Glioblastoma: Correlation with Response to Chemoradiation and Overall Survival
por: Soni, Priyanka, et al.
Publicado: (2017)

Evaluation of Progression-Free Survival and Overall Survival of Epidermal Growth Factor Receptor-Positive Metastatic Lung Adenocarcinoma Patients Treated with Erlotinib
por: Shahriari, Saeedeh, et al.
Publicado: (2022)

The Prognostic Nutritional Index before durvalumab after chemoradiation predict the overall survival in patients with stage III non-small cell lung cancer
por: Matsuura, Shun, et al.
Publicado: (2023)

Neutrophilia as a biomarker for overall survival in newly diagnosed high-grade glioma patients undergoing chemoradiation
por: Schernberg, Antoine, et al.
Publicado: (2018)

Surgery provides improved overall survival in surgically fit octogenarians with esophageal cancer after chemoradiation therapy
por: Del Calvo, Haydee, et al.
Publicado: (2021)

Effect of Waiting Time from Pathological Diagnosis to Definitive Concurrent Chemoradiation for Cervical Cancer on Overall Survival
por: Noh, Kyoung Won, et al.
Publicado: (2022)

Erlotinib and Concurrent Chemoradiation in Pretreated NSCLC Patients: Radiobiological Basis and Clinical Results
por: Ramella, Sara, et al.
Publicado: (2013)

Stereotactic body radiation therapy is associated with improved overall survival compared to chemoradiation or radioembolization in the treatment of unresectable intrahepatic cholangiocarcinoma
por: Sebastian, Nikhil T., et al.
Publicado: (2019)

Survival After Induction Chemotherapy and Chemoradiation Versus Chemoradiation and Adjuvant Chemotherapy for Locally Advanced Rectal Cancer
por: Kim, Jin K, et al.
Publicado: (2022)

Rates of Overall Survival and Intracranial Control in the Magnetic Resonance Imaging Era for Patients With Limited-Stage Small Cell Lung Cancer With and Without Prophylactic Cranial Irradiation
por: Pezzi, Todd A., et al.
Publicado: (2020)

Clinical outcome and predictors of survival and pneumonitis after stereotactic ablative radiotherapy for stage I non-small cell lung cancer
por: Chang, Joe Y, et al.
Publicado: (2012)

Nomogram for predicting overall survival in stage II‐III colorectal cancer
por: Liu, Jungang, et al.
Publicado: (2020)

FDG uptake correlates with recurrence and survival after treatment of unresectable stage III non-small cell lung cancer with high-dose proton therapy and chemotherapy
por: Xiang, Zuo-Lin, et al.
Publicado: (2012)

Five-year overall survival following chemoradiation therapy for locally advanced cervical carcinoma in women living with and without HIV infection in Botswana
por: MacDuffie, Emily, et al.
Publicado: (2021)

HO‐1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy
por: Akaishi, Ryujiro, et al.
Publicado: (2021)

Adjuvant chemoradiation in pancreatic cancer: impact of radiotherapy dose on survival
por: Morganti, Alessio G., et al.
Publicado: (2019)

Correlation of skin rash and overall survival in patients with pancreatic cancer treated with gemcitabine and erlotinib – results from a non-interventional multi-center study
por: Westphalen, C. Benedikt, et al.
Publicado: (2020)

Impact of Adjuvant Therapy Type on Survival in Stage II/III Rectal Cancer Without Preoperative Chemoradiation: A Korean Multicenter Retrospective Study
por: Kang, Byung Mo, et al.
Publicado: (2018)

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer
por: Kim, Jin-Soo, et al.
Publicado: (2015)

Three-Year Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC—Update from PACIFIC
por: Gray, Jhanelle E., et al.
Publicado: (2019)

Duration of chemotherapy prior to chemoradiation affects survival outcomes for resected stage I‐II or unresected stage III pancreatic cancer
por: Ma, Sung J., et al.
Publicado: (2019)

Radiomic Phenotypes for Improving Early Prediction of Survival in Stage III Non-Small Cell Lung Cancer Adenocarcinoma after Chemoradiation
por: Luna, José Marcio, et al.
Publicado: (2022)

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors
por: Mehrotra, Meenakshi, et al.
Publicado: (2017)

The impact of previous cancer on overall survival of bladder cancer patients and the establishment of nomogram for overall survival prediction
por: Wang, Zhengquan, et al.
Publicado: (2020)

PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer
por: Constanzo, Jerfiz D., et al.
Publicado: (2016)

Functional connectivity within glioblastoma impacts overall survival
por: Daniel, Andy G S, et al.
Publicado: (2020)

Incidence and Overall Survival of Malignant Ameloblastoma
por: Rizzitelli, Alexandra, et al.
Publicado: (2015)

Inflammatory breast cancer appearance at presentation is associated with overall survival
por: Balema, Wintana, et al.
Publicado: (2021)

Overall survival of patients with EGFR mutation-positive non-small-cell lung cancer treated with erlotinib, gefitinib or afatinib under drug programmes in Poland – real-world data
por: Brzozowska, Melania, et al.
Publicado: (2019)

Outcomes of re-irradiation for brain recurrence after prophylactic or therapeutic whole-brain irradiation for small cell lung Cancer: a retrospective analysis
por: Suzuki, Ryoko, et al.
Publicado: (2018)

Pathologic complete response and overall survival in breast cancer subtypes in stage III inflammatory breast cancer
por: van Uden, Dominique J. P., et al.
Publicado: (2019)

Magnetic Resonance Imaging Derived Biomarkers of IDH Mutation Status and Overall Survival in Grade III Astrocytomas
por: Feraco, Paola, et al.
Publicado: (2020)

Incremental Value of Radiomics in 5-Year Overall Survival Prediction for Stage II–III Rectal Cancer
por: Nie, Ke, et al.
Publicado: (2022)

Neutrophil to lymphocyte ratio can predict overall survival in patients with stage II to III colorectal cancer
por: Cho, Yerim, et al.
Publicado: (2023)

A methylomics-associated nomogram predicts the overall survival risk of stage III to IV ovarian cancer
por: Wei, Xuan, et al.
Publicado: (2023)

Is there hope in improving 5-year overall survival?—review of 5-year overall survival data from KEYNOTE-001
por: Akingbemi, Wisdom, et al.
Publicado: (2020)

Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib
por: Lee, Chia-Han, et al.
Publicado: (2022)

Cancer associated macrophage-like cells and prognosis of esophageal cancer after chemoradiation therapy
por: Gironda, Daniel J., et al.
Publicado: (2020)

Long-term survival after concurrent chemoradiation therapy for esophageal cancer with tracheal invasion
por: Cho, Joon Hyun, et al.
Publicado: (2015)

Long -Term Survival in Stage IV Esophageal Adenocarcinoma with Chemoradiation and Serial Endoscopic Cryoablation
por: Spiritos, Zachary, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u5j7b7t940da6m2k0uk8ddbo10