Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching

TRPV3 is a thermosensitive ion channel primarily expressed in epithelial tissues of the skin, nose, and tongue. The channel has been implicated in environmental thermosensation, hyperalgesia in inflamed tissues, skin sensitization, and hair growth. Although transient receptor potential (TRP) channel...

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Detalles Bibliográficos
Autores principales: Billen, Bert, Brams, Marijke, Debaveye, Sarah, Remeeva, Alina, Alpizar, Yeranddy A., Waelkens, Etienne, Kreir, Mohamed, Brüggemann, Andrea, Talavera, Karel, Nilius, Bernd, Voets, Thomas, Ulens, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432310/
https://www.ncbi.nlm.nih.gov/pubmed/25829496
http://dx.doi.org/10.1074/jbc.M114.628925

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