A cardiorenal-pulmonary-cutaneous-muscle syndrome

Anti-synthetase syndrome is a relatively recently described auto-immune disease characterized by auto-antibodies to enzymes that acetylate transfer RNA (tRNA). Interstitial pulmonary disease and inflammatory myopathy are regular findings. Our patient also exhibited a lupus-like glomerulonephritis. A...

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Detalles Bibliográficos
Autores principales: Schöpp, Sebastian, Elitok, Saban, Bieringer, Markus, Schneider, Wolfgang, Luft, Friedrich C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432453/
https://www.ncbi.nlm.nih.gov/pubmed/26019850
http://dx.doi.org/10.1093/ckj/sft017
Descripción
Sumario:Anti-synthetase syndrome is a relatively recently described auto-immune disease characterized by auto-antibodies to enzymes that acetylate transfer RNA (tRNA). Interstitial pulmonary disease and inflammatory myopathy are regular findings. Our patient also exhibited a lupus-like glomerulonephritis. An important clue was the presence of ‘mechanics’ hands. Nephrologists need to be aware of this syndrome.

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