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Dynamic Changes in DNA Methylation in Ischemic Tolerance

Epigenetic mediators of gene expression are hypothesized to regulate transcriptomic responses to preconditioning ischemia and ischemic tolerance. Here, we utilized a methyl-DNA enrichment protocol and sequencing (ChIP-seq) to identify patterns of DNA methylation in an established model of ischemic t...

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Detalles Bibliográficos
Autores principales: Meller, Robert, Pearson, Andrea, Simon, Roger P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432797/
https://www.ncbi.nlm.nih.gov/pubmed/26029158
http://dx.doi.org/10.3389/fneur.2015.00102