Cargando…
The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link
Numerous epidemiological and pre-clinical studies have demonstrated that the insulin/insulin-like growth factor (IGF) system plays a key role in the development and progression of several types of cancer. Insulin/IGF signaling, in cooperation with chronic low-grade inflammation, is also an important...
Autores principales: | Bowers, Laura W., Rossi, Emily L., O’Flanagan, Ciara H., deGraffenried, Linda A., Hursting, Stephen D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432799/ https://www.ncbi.nlm.nih.gov/pubmed/26029167 http://dx.doi.org/10.3389/fendo.2015.00077 |
Ejemplares similares
-
Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway
por: Bowers, Laura W., et al.
Publicado: (2015) -
Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression
por: Bowers, Laura W, et al.
Publicado: (2013) -
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor–Intrinsic and Extrinsic Factors
por: Doerstling, Steven S., et al.
Publicado: (2017) -
An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer
por: McClellan, Bryan, et al.
Publicado: (2022) -
When less may be more: calorie restriction and response to cancer therapy
por: O’Flanagan, Ciara H., et al.
Publicado: (2017)