Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion

The membrane localization and activation of cytoskeletal protein talin are key steps to initiate integrin transmembrane receptors activation, which mediates many cellular adhesive responses such as cell migration, spreading, and proliferation. RIAM, a membrane anchor and small GTPase RAP1 effector,...

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Detalles Bibliográficos
Autores principales: Yang, Jun, Zhu, Liang, Zhang, Hao, Hirbawi, Jamila, Fukuda, Koichi, Dwivedi, Pallavi, Liu, Jianmin, Byzova, Tatiana, Plow, Edward F., Wu, Jinhua, Qin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432866/
https://www.ncbi.nlm.nih.gov/pubmed/25520155
http://dx.doi.org/10.1038/ncomms6880

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