Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma

A 66-year-old man initially underwent appendectomy and cytoreductive surgery for a low-grade appendiceal mucinous neoplasm with pseudomyxoma peritonei. One and a half years later, multiple disseminated lesions developed in rectus abdominis muscle and peritoneal cavity. Biopsy showed histopathologica...

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Autores principales: Chen, Yu-Nung, Lee, Jie-Jen, Cheng, Shih-Ping, Tsai, Chung-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432903/
https://www.ncbi.nlm.nih.gov/pubmed/26015826
http://dx.doi.org/10.14740/jocmr2178w
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author Chen, Yu-Nung
Lee, Jie-Jen
Cheng, Shih-Ping
Tsai, Chung-Hsin
author_facet Chen, Yu-Nung
Lee, Jie-Jen
Cheng, Shih-Ping
Tsai, Chung-Hsin
author_sort Chen, Yu-Nung
collection PubMed
description A 66-year-old man initially underwent appendectomy and cytoreductive surgery for a low-grade appendiceal mucinous neoplasm with pseudomyxoma peritonei. One and a half years later, multiple disseminated lesions developed in rectus abdominis muscle and peritoneal cavity. Biopsy showed histopathological transformation to sarcomatoid carcinoma. This case illustrates that evolution of low-grade pseudomyxoma peritonei to high-grade carcinoma truly develops in some patients. The development of this dedifferentiation appears associated with aggressive behavior and poor clinical outcome.
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spelling pubmed-44329032015-05-26 Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma Chen, Yu-Nung Lee, Jie-Jen Cheng, Shih-Ping Tsai, Chung-Hsin J Clin Med Res Case Report A 66-year-old man initially underwent appendectomy and cytoreductive surgery for a low-grade appendiceal mucinous neoplasm with pseudomyxoma peritonei. One and a half years later, multiple disseminated lesions developed in rectus abdominis muscle and peritoneal cavity. Biopsy showed histopathological transformation to sarcomatoid carcinoma. This case illustrates that evolution of low-grade pseudomyxoma peritonei to high-grade carcinoma truly develops in some patients. The development of this dedifferentiation appears associated with aggressive behavior and poor clinical outcome. Elmer Press 2015-07 2015-05-08 /pmc/articles/PMC4432903/ /pubmed/26015826 http://dx.doi.org/10.14740/jocmr2178w Text en Copyright 2015, Chen et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chen, Yu-Nung
Lee, Jie-Jen
Cheng, Shih-Ping
Tsai, Chung-Hsin
Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title_full Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title_fullStr Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title_full_unstemmed Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title_short Transformation of Low-Grade Mucinous Neoplasm of the Appendix With Pseudomyxoma Peritonei to High-Grade Sarcomatoid Carcinoma
title_sort transformation of low-grade mucinous neoplasm of the appendix with pseudomyxoma peritonei to high-grade sarcomatoid carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432903/
https://www.ncbi.nlm.nih.gov/pubmed/26015826
http://dx.doi.org/10.14740/jocmr2178w
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