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GATA4 transgenic mice as an in vivo model of congenital heart disease

Our previous study indicated that 8 patients from a family with a history of congenital heart disease had simple atrial septal defect (ASD) and carried the same mutation at codon 310 in the GATA4 gene. In the present study, to identify the functional defects caused by this mutation in an in vivo mod...

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Detalles Bibliográficos
Autores principales: HAN, HUA, CHEN, YU, LIU, GANG, HAN, ZENGQIANG, ZHAO, ZHOU, TANG, YIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432925/
https://www.ncbi.nlm.nih.gov/pubmed/25873328
http://dx.doi.org/10.3892/ijmm.2015.2178