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Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions

Uncoupling protein 2 (UCP2) regulates the production of mitochondrial reactive oxygen species (ROS) and cellular energy transduction under physiological or pathological conditions. In this study, we aimed to determine whether mitochondrial UCP2 plays a protective role in cardiomyocytes under septic...

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Detalles Bibliográficos
Autores principales: ZHENG, GUILANG, LYU, JUANJUAN, LIU, SHU, HUANG, JINDA, LIU, CUI, XIANG, DAN, XIE, MEIYAN, ZENG, QIYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432931/
https://www.ncbi.nlm.nih.gov/pubmed/25873251
http://dx.doi.org/10.3892/ijmm.2015.2177