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Domain atrophy creates rare cases of functional partial protein domains

BACKGROUND: Protein domains display a range of structural diversity, with numerous additions and deletions of secondary structural elements between related domains. We have observed a small number of cases of surprising large-scale deletions of core elements of structural domains. We propose a new c...

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Detalles Bibliográficos
Autores principales: Prakash, Ananth, Bateman, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432964/
https://www.ncbi.nlm.nih.gov/pubmed/25924720
http://dx.doi.org/10.1186/s13059-015-0655-8

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