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Domain atrophy creates rare cases of functional partial protein domains
BACKGROUND: Protein domains display a range of structural diversity, with numerous additions and deletions of secondary structural elements between related domains. We have observed a small number of cases of surprising large-scale deletions of core elements of structural domains. We propose a new c...
Autores principales: | Prakash, Ananth, Bateman, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432964/ https://www.ncbi.nlm.nih.gov/pubmed/25924720 http://dx.doi.org/10.1186/s13059-015-0655-8 |
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